Skin cell model advances study of genetic mutation linked to heart disease, stroke risk

http://ift.tt/2tT45KJ Using a new skin cell model, researchers have overcome a barrier that previously prevented the study of living tissue from people at risk for early heart disease and stroke. This research could lead to a new understanding of disease progression in aortic aneurysm — ballooning of the large artery in the chest that carries blood from the heart to the body.

Key player in heart enlargement identified

http://ift.tt/2tShkey The heart is a dynamic muscle that grows and shrinks in response to stressors such as exercise and disease. The secret to its malleability lies in individual cells, which get bigger or smaller depending on the heart’s needs. A new study of mouse hearts reveals a previously unknown mechanism by which heart cells control their size by ramping up or stopping the production of a key factor called PABPC1.