http://bit.ly/2LefK3m Infants less than six months old with Noonan Syndrome, hypertrophic cardiomyopathy and congestive heart failure normally have a poor prognosis, with a one-year survival rate of 34 percent. In the new study, doctors used Trametinib to try to treat NS in two patients. They observed dramatic improvement of clinical and cardiac status in the patients only three months after treatment.
http://bit.ly/2GKK9Rt Researchers have combined their expertise to develop a new type of microscope. The revolutionary new light-field microscopy system makes it possible to study fast biological processes, creating up to 200 3D images per second. Initial tests have already delivered new insights into the movement of blood cells in a heart.
http://bit.ly/2Vwc0hH People with good vision despite having center-involved diabetic macular edema can safely forego immediate treatment of their eye condition as long as they are closely monitored, and treatment begins promptly if vision worsens, according to clinical trial results.
http://bit.ly/2VAMoQA First Genome-Wide Association Study for Type 2 diabetes discovers seven genetic variants associated with the disease in young people.
http://bit.ly/2vuVijU Researchers propose PGE exerts adenosine-mediated effects on brainstem mechanisms of respiratory control, which may lead to destabilization of breathing in human infants undergoing treatment for congenital heart disease. Prostaglandin’s effects could be mediated thorough microglia, and caffeine could be a convenient treatment to prevent respiratory instability in infants receiving PGE1 infusion.
http://bit.ly/2L8u9Oj Newborns with life-threatening congenital heart disease often need open-heart surgery with cardiopulmonary bypass, which carries a risk of damaging the brain. Critically ill newborns who are placed on ECMO are at even higher risk for brain injury. A new study, performed in a large animal model, suggests that adding a dash of hydrogen to the usual mix of respiratory gases could further protect babies’ brains. The researchers are now planning a small safety trial.
http://bit.ly/2GR3MII New research shows that individuals with obesity who commute by car have a 32% higher risk of early death, from any cause, compared with those individuals with a normal weight and commute via cycling and walking.