Towards a safe and scalable cell therapy for type 1 diabetes by simplifying beta cell differentiation

http://ift.tt/2vYJ5Dn With the vision of providing a cell therapy for type 1 diabetes patients, scientists have identified a unique cell surface protein present on human pancreatic precursor cells providing for the first time a molecular handle to purify the cells whose fate is to become cells of the pancreas — including insulin-producing cells.

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AAP counsels pediatricians to focus on clusters of cardiometabolic risk factors to help obese kids

http://ift.tt/2vbydF4 Since frameworks used to identify adults at heightened risk for such complications are a poor fit for kids, the American Academy of Pediatrics now recommends that pediatricians instead focus on clusters of cardiometabolic risk factors that are associated with obesity.

Medalist study underlines importance of glucose control in adults with Type 1 diabetes

http://ift.tt/2vbrzOW Findings of the latest study of the Joslin 50-Year Medalists, who have had type 1 diabetes for at least 50 years, re-emphasize the importance of good blood glucose control and exercise in reducing complications and mortality rates for these older individuals.

Five vascular diseases linked to one common genetic variant

http://ift.tt/2uCiddB Genome-wide association studies have implicated a common genetic variant in chromosome 6p24 in coronary artery disease, as well as four other vascular diseases: migraine headache, cervical artery dissection, fibromuscular dysplasia, and hypertension. However, it has not been clear how this polymorphism affects the risk for so many diseases. Researchers show how this DNA variant enhances the activity of a gene called endothelin-1, which is known to promote vasoconstriction and hardening of the arteries.